389 Results for "

Grevillea robusta A. Cunn. ex R. Br.

" in MedChemExpress (MCE) Product Catalog:
Products (389)

389 Results for "Grevillea robusta A. Cunn. ex R. Br." in MCE Product Catalog:

39
39 Publications Verification
製品番号: HY-12306
CAS 番号: 76939-46-3
純度:  99.91%
別名: 8-Br-Camp sodium salt
Target:  

PKA Apoptosis

研究分野:  

Cancer

8-Bromo-cAMP sodium (8-Br-Camp) sodium salt, a cyclic AMP analog, is an activator of cyclic AMP-dependent protein kinase (PKA). 8-Bromo-cAMP sodium salt has anti-proliferative and apoptotic effects against cancer cells .
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39
39 Publications Verification
製品番号: HY-12306A
CAS 番号: 23583-48-4
純度:  99.48%
別名: 8-Br-Camp
Target:  

PKA Apoptosis

研究分野:  

Cancer

8-Bromo-cAMP (8-Br-Camp), a cyclic AMP analog, is an activator of cyclic AMP-dependent protein kinase (PKA). 8-Bromo-cAMP has anti-proliferative and apoptotic effects against cancer cells .
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9
9 Cited Publications
製品番号: HY-129393
CAS 番号: 2239273-34-6
純度:  99.67%
別名: AB928
Target:  

Adenosine Receptor

研究分野:  

Inflammation/Immunology Cancer

Etrumadenant (AB928) is an orally bioavailable, selective dual adenosine receptor (A2aR/A2bR) antagonist. Etrumadenant relieves adenosine-mediated immune suppression. Etrumadenant has immunomodulatory and antitumor activities .
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4
4 Cited Publications
製品番号: HY-B0566
CAS 番号: 23256-50-0
別名: BR-750; Wy8678 acetate
Guanabenz (Acetate) (BR-750) is an alpha-2 selective adrenergic agonist used as an antihypertensive agent.
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4
4 Cited Publications
製品番号: HY-B0780
CAS 番号: 247257-48-3
別名: BR-A-657
Fimasartan (BRA-657) is an orally effective angiotensin receptor AT1 non-peptide antagonist. Fimasartan has antihypertensive effects. Fimasartan improves neuroinflammation and brain injury mediated by NLRP3 inflammatome after intracerebral hemorrhage, and has neuroprotective effect. Fimasartan inhibits the expression of inducible nitric oxide synthase through the inactivation of NF-κB and activator protein-1 .
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3
3 Cited Publications
製品番号: HY-D1396
CAS 番号: 2387906-44-5
研究分野:  

Others

Br-DAPI is a marker dye in DAPI series. DAPI is a fluorescent dye that binds strongly to DNA. It binds to the AT base pair of the double-stranded DNA minor groove, and one DAPI molecule can occupy three base pair positions. The fluorescence intensity of DAPI molecules bound to double-stranded DNA is increased by about 20 times, and it is commonly observed with fluorescence microscopy, and the amount of DNA can be determined based on the intensity of fluorescence. DAPI cannot penetrate intact cell membranes and is commonly used for staining damaged and fixed cells . Storage: Keep away from light.
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3
3 Cited Publications
製品番号: HY-103169
CAS 番号: 316173-57-6
純度:  99.94%
Target:  

Adenosine Receptor

研究分野:  

Neurological Disease

SCH442416 is a potent, selective and brain-penetrant antagonist of adenosine A2A receptor (A2AR), with Kis of 0.048 and 0.5 nM for human and rat A2AR respectively. SCH442416 displays more than 23000-fold selectivity over A1R, A2BR, and A3R (Ki=1111, 10000, and 10000 nM, respectively). SCH442416 can be used for imaging of adenosine A2A receptors in rat and primate brain .
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2
2 Cited Publications
製品番号: HY-B0460
CAS 番号: 411207-31-3
別名: BA-679 BR monohydrate
Target:  

mAChR

研究分野:  

Inflammation/Immunology

Tiotropium bromide monohydrate (BA-679 BR monohydrate) is a long-acting anticholinergic bronchodilator. Tiotropium bromide monohydrate blocks the action of acetylcholine at muscarinic M1, M2, and M3 receptors, prevents bronchoconstriction, and dilates bronchial airways. Tiotropium bromide monohydrate is applicable to research related to chronic obstructive pulmonary disease and asthma .
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2
2 Cited Publications
製品番号: HY-17360
CAS 番号: 136310-93-5
別名: BA679 BR
Target:  

mAChR

研究分野:  

Inflammation/Immunology

Tiotropium bromide (BA-679 BR) is a long-acting anticholinergic bronchodilator. Tiotropium bromide blocks the action of acetylcholine at muscarinic M1, M2, and M3 receptors, prevents bronchoconstriction, and dilates bronchial airways. Tiotropium bromide is applicable to research related to chronic obstructive pulmonary disease and asthma .
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2
2 Cited Publications
製品番号: HY-121161A
CAS 番号: 280129-83-1
純度:  99.71%
Target:  

Cytochrome P450

研究分野:  

Others

Brassinazole is a selective triazole-type brassinosteroid (BR) biosynthesis inhibitor. Brassinazole is used for regulating plant growth and development .
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2
2 Cited Publications
製品番号: HY-12524
CAS 番号: 188011-69-0
純度:  99.96%
別名: Abrasin
Target:  

GSK-3

研究分野:  

Others

Bikinin is a non-steroidal, ATP-competitive inhibitor of plant GSK-3/Shaggy-like kinases and activates BR (brassinosteroids) signaling.
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2
2 Cited Publications
製品番号: HY-103355
CAS 番号: 145084-28-2
純度:  99.87%
Target:  

CCR

研究分野:  

Metabolic Disease

YM022 is a highly potent, selective and orally active gastrin/cholecystokinin (CCK)-B receptor (CCK-BR) antagonist. YM022 shows the Ki values of 68 pM and 63 nM for CCK-B and CCK-A receptor, respectively . YM022 can inhibit gastrin-induced gastric acid secretion and histidine decarboxylase activation in vivo .
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1
1 Cited Publications
製品番号: HY-W007803
CAS 番号: 164365-88-2
Target:  

PROTAC Linkers

研究分野:  

Cancer

Boc-NH-C4-Br is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs .
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1
1 Cited Publications
製品番号: HY-W404002
CAS 番号: 2505339-54-6
研究分野:  

Metabolic Disease

BR102910 is a selective fibroblast activation protein (FAP) inhibitor with the IC50 of 2 nM. BR102910 also inhibits prolyl oligopeptidase (PREP) with the IC50 of 49.00 μM. BR102910 can be used for the researchof type 2
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1
1 Cited Publications
製品番号: HY-137640C
CAS 番号: 925456-59-3
Target:  

PKA

研究分野:  

Inflammation/Immunology Cancer

Rp-8-Br-cAMPS sodium is an analog of cAMP and an inhibitor of PKA. Rp-8-Br-cAMPS sodium occupies cAMP binding sites on PKA type I regulatory subunits, thereby preventing PKA dissociation and activation. Rp-8-Br-cAMPS sodium can be used in the study of tumors and retrovirus-induced immune deficiency. Rp-8-Br-cAMPS sodium also inhibits insulin secretion .
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1
1 Cited Publications
製品番号: HY-135110
CAS 番号: 208445-06-1
別名: Rp-8-bromo-Cyclic GMPS sodium
研究分野:  

Metabolic Disease

Rp-8-Br-cGMPS (Rp-8-bromo-Cyclic GMPS) sodium salt is a potent Ca 2+-ATPase activator. Rp-8-Br-cGMPS is also an agonist of the rod CNG channel and an inhibitor of PKG. Rp-8-Br-cGMPS sodium salt mediates cytosolic Ca 2+ reduction by activating Ca 2+-ATPase and subsequently removing Ca 2+ from the cell .
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1
1 Cited Publications
製品番号: HY-P2671
CAS 番号: 39024-57-2
研究分野:  

Cancer

[Leu15]-Gastrin I (human) is a Gastrin I, human (HY-P1097) peptide hormone derivative, which is trophic for normal gastrointestinal epithelium. Gastrin stimulates growth of gastric adenocarcinoma (gastric cancer) through G-protein-coupled receptor called the cholecystokinin (CCK) or cholecystokinin-B receptors (CCK-BR) that are overexpressed in this malignancy. [Leu15]-Gastrin I (human) is promising for research of gastric cancer .
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1
1 Cited Publications
製品番号: HY-P75667
純度:  ≥ 80%, as determined by reducing SDS-PAGE.
別名: CDH12; cadherin 12, type 2 (N-cadherin 2); cadherin-12; Br cadherin; CDHB; Br-cadherin; N-cadherin 2; brain cadherin; brain-cadherin; neuronal cadherin 2; neural type cadherin 2; cadherin, neural type, 2; FLJ34857;
Species:  
Source:  
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1
1 Cited Publications
製品番号: HY-Y0678
CAS 番号: 621-23-8
別名: TRIMETHYL PHLOROGLUCINOL
1,3,5-Trimethoxybenzene (TRIMETHYL PHLOROGLUCINOL) is an electrophilic substitution reaction substrate targeting free chlorine (Cl +) and free bromine (Br +). 1,3,5-Trimethoxybenzene has highly selective electrophilic addition characteristics. By capturing halogens, it undergoes specific substitution reactions to generate stable halogenated products. 1,3,5-Trimethoxybenzene can not only quench residual oxidants, but also quantify the halogen concentration by detecting the product without affecting the stability of redox-sensitive disinfection byproducts (DBPs). 1,3,5-Trimethoxybenzene is mainly used in water quality testing and quantitative analysis of free chlorine/bromine in water. At the same time, in phytochemistry, it is a key component of rose fragrance and participates in the study of pollination attraction mechanism .
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製品番号: HY-W011561
CAS 番号: 142356-33-0
Target:  

ADC Linkers

研究分野:  

Cancer

Boc-NH-C6-Br is a non-cleavable linker used for antibody-drug conjugates (ADC) .
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